Fair Game - Stephanie Piro's daily comic with a twist!
Falling Down Productions - Downfall is a comic about a group of displaced Minneapolis city kids attending school in small town. Also features Half Truths.
Falling Dream - A weekly web comic strip in color, by Greg Tuft. Featuring ad parodies, internet and political humor, and social satire.
The Family Monster - Features a gallery, the characters, and archives. By Josh Shalek.
The Fan - Taking place in Iraq and featuring the adventures of two soldiers Dehn and Kensou X, this series offers a way for its creators to keep sane from the middle of a war.
Fanboy Almanac - Weekly about the life and times of four average comic book/sci-fi/pop culture fanboys.
FANS - The story of a few science-fiction fans caught in real science-fiction adventures.
Farcus - Daily panel comic by David Waislass and Gordon Goulthart. Featuring daily color cartoon (with 2-week archive), postcards, and chats with the creators.
Fat Jesus - The adventures of a obese defective clone of Jesus.
Faustian Deal - Chronicles the perilous balance between redemption and damnation for two dot-commers and the demons out for their souls.
Fergo and Enrique - Two animal children learn about life; also, single-panel gag cartoons. By Robert M. Blake.
Few and Far Between - Regularly-updated comic by Joda Thayer with a cast of child-like characters tangled up in the curtain that divides the mythic from the mundane. Contains calendar to download, character profiles and archive.
FileFish Comics - Follows the students of College University in their quest to fend off boredom and save the world from the town's oppressive right-wing newspaper and its plans to rule the world.
Fishead Tackle - Features daily cartoons, stories, tips and pictures about fishing.
Fishy Comics - Australian strip by Richard Jones, all about fishing.
Flail - Comic about the semi-realistic lives of some people - includes past strips.
Flash Gordon - This star-spanning adventure was created by Alex Raymond in 1934. Still great fun.
Frank, Hank and Charles - The adventures of three sort-of friends. Features an archive, cast and about the comic.
Frankenstudent - A young Frankenstein comes to America - and enters the third grade. Online comic updated Mon-Thur. Site also contains unrelated single-panel comic updated Fridays.
Fray, Brian - Portfolio of panels and humorous illustration by the cartoonist.
Fred and Frank - The crazy cartoon adventures of two soldiers stationed in Germany from 1979 until 1992. Written and illustrated by Charles Kaufman.
Freddy and Co - A comedic webtoon featuring famous people and talking cats and trees. As styled by a teen.
Freex - About the strange lives of three quite insane guys.
Friendbear - A copy/paste bear and his surreal friends endure countless existential nonsensical adventures, and then have snacks.
From The Desk Of - A cartoon site that sometimes has no actual drawings.
FS666: the Fatsquad - The official home of the Fatsquad, NH's most controversial comic strip that doesn't care who they make mad.
Full Contact Origami - Three guys. One computer. Lots of free time. Get the picture? by Truthsnark.
Fun by Kaz - Cartoons signed "Kaz" have appeared in magazines and newspapers since 1950 (Saturday Evening Post, and Esquire, 26 book collections). Features cartoons and HeadLines acrostic-type puzzles, including a Cartoon of the Week and HeadLines of the Week.
Functionbad.com - A comic strip about real life events. Updated regularly. Includes archives and guest art.